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Article

High prevalence of triazole-resistant Aspergillus fumigatus sensu stricto in an Argentinean cohort of patients with cystic fibrosis.

Mycoses - 1 Sept 2020

Brito Devoto Tomás, Hermida-Alva Katherine, Posse Gladys, Finquelievich Jorge L, García-Effrón Guillermo, Cuestas María L

Abstract excerpt

BACKGROUND: Triazole resistance in Aspergillus fumigatus sensu stricto due to mutations in the cyp51A gene has been widely reported. Data from Argentina, and particularly from cystic fibrosis (CF) patients, are limited. OBJECTIVES: To investigate the prevalence and molecular mechanisms of azole resistance in A. fumigatus sensu stricto recovered from this population. METHODS: Ninety-three A. fumigatus isolates...

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PMID: 32648614
DOI: 10.1111/myc.13139

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