Article
Prevalence and molecular characterization of azole resistance in Aspergillus spp. isolates from German cystic fibrosis patients.
The Journal of antimicrobial chemotherapy - 1 Jun 2014
Fischer J, van Koningsbruggen-Rietschel S, Rietschel E, Vehreschild M J G T, Wisplinghoff H, Krönke M, Hamprecht A
Abstract excerpt
OBJECTIVES: Aspergillus spp. are the most frequently isolated filamentous fungi in the sputum of patients with cystic fibrosis (CF). Resistance to the azoles, the mainstay of current antifungal therapy, has been increasingly observed worldwide, but few data are available on the resistance of Aspergillus spp. in German CF patients. This study investigated the epidemiology of Aspergillus spp. and the molecular...
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