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Article

Genome-wide analysis of high-risk primary brain cancer pedigrees identifies PDXDC1 as a candidate brain cancer predisposition gene.

Neuro-oncology - 25 Feb 2021

Cannon-Albright Lisa A, Farnham James M, Stevens Jeffrey, Teerlink Craig C, Palmer Cheryl A, Rowe Kerry, Cessna Melissa H, Blumenthal Deborah T

Abstract excerpt

BACKGROUND: There is evidence for an inherited contribution to primary brain cancer. Linkage analysis of high-risk brain cancer pedigrees has identified candidate regions of interest in which brain cancer predisposition genes are likely to reside. METHODS: Genome-wide linkage analysis was performed in a unique set of 11 informative, extended, high-risk primary brain cancer pedigrees identified in a population...

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Identifiers

PMID: 32644145
DOI: 10.1093/neuonc/noaa161
PMCID: PMC7906047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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