Article
Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Jun 2020
Pool René, Hagenbeek Fiona A, Hendriks Anne M, van Dongen Jenny, Willemsen Gonneke, de Geus Eco, Willems van Dijk Ko, Verhoeven Aswin, Suchiman H Eka, Beekman Marian, Slagboom P Eline, Harms Amy C, Hankemeier Thomas, Boomsma Dorret I
Abstract excerpt
Metabolites are small molecules involved in cellular metabolism where they act as reaction substrates or products. The term 'metabolomics' refers to the comprehensive study of these molecules. The concentrations of metabolites in biological tissues are under genetic control, but this is limited by environmental factors such as diet. In adult mono- and dizygotic twin pairs, we estimated the contribution of genetic...
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