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FOXP3 Genetic Variants Do Not Impact Circulating and Cervical Interleukin-10 Levels in Human Papillomavirus Infection in Women.

Viral immunology - 1 Dec 2020

Cezar-Dos-Santos Fernando, Berti Fernanda Costa Brandão, Okuyama Nádia Calvo Martins, Trugilo Kleber Paiva, Simão Andréa Name Colado, Watanabe Maria Angélica Ehara, Brajão de Oliveira Karen

Abstract excerpt

Regulatory T cell (Treg) lineage plays a central role in inflammation and autoimmunity control. Interleukin-10 (IL-10) has been described as a pleiotropic cytokine that is mainly released by CD4+ CD25+ FOXP3+ Treg cells and has a potent immunosuppressive activity. Forkhead box P3 (FOXP3) transcription factor expression is crucial for Treg to function as a suppressor cell, and FOXP3 gene single nucleotide variants...

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PMID: 32634048
DOI: 10.1089/vim.2020.0040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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