Article
Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma.
PloS one - 9 Apr 2008
Rebetz Johan, Tian Dongping, Persson Annette, Widegren Bengt, Salford Leif G, Englund Elisabet, Gisselsson David, Fan Xiaolong
Abstract excerpt
BACKGROUND: While neurosphere- as well as xenograft tumor-initiating cells have been identified in gliomas, the resemblance between glioma cells and neural stem/progenitor cells as well as the prognostic value of stem/progenitor cell marker expression in glioma are poorly clarified. METHODOLOGY/PRINCIPAL FINDINGS: Viable glioma cells were characterized for surface marker expression along the glial genesis...
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