Article
Predispositions to Lymphoma: A Practical Review for Genetic Counselors.
Journal of genetic counseling - 1 Dec 2016
Similuk Morgan, Rao V Koneti, Churpek Jane, Lenardo Michael
Abstract excerpt
This review provides a synopsis for genetic counselors of the major concepts of lymphoma predisposition: genomic instability, immune deficiency, inappropriate lymphoproliferation, and chronic antigen stimulation. We discuss syndromes typifying each of these mechanisms. Importantly, our review of the genetic counseling literature reveals sparse discussion of genetically-based immune-mediated lymphoma...
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