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Article

Insights into germline predisposition to pediatric lymphoid malignancies.

Leukemia - 1 Nov 2025

Thapa Roshina, Nichols Kim E, Sharma Richa

Abstract excerpt

Hematopoietic malignancies (HM) represent the most common form of pediatric cancer with lymphoid malignancies being the predominant subtype in kids. The majority of lymphoid malignancies are proposed to occur sporadically with environmental, infectious and inflammatory triggers impacting oncogenesis in ways that are not yet fully understood. With the increased adoption of germline genetic testing in children with...

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Identifiers

PMID: 40925926
DOI: 10.1038/s41375-025-02750-z
PMCID: PMC12589141

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