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Article

Somatic Variants: New Kids on the Block in Human Immunogenetics.

Trends in genetics : TIG - 1 Dec 2019

Van Horebeek L, Dubois B, Goris A

Abstract excerpt

Somatic variants are not inherited but acquired during an individual's lifetime, and individuals are increasingly considered as complex mosaics of genetically distinct cells. Whereas this concept is long-recognized in cancer, this review focuses on the growing role of somatic variants in immune cells in nonmalignant immune-related disorders, such as primary immunodeficiency and autoimmune diseases. Older case...

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Identifiers

PMID: 31668909
DOI: 10.1016/j.tig.2019.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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