Article
Cadherin-related Family Member 3 Genetics and Rhinovirus C Respiratory Illnesses.
American journal of respiratory and critical care medicine - 1 Mar 2018
Bønnelykke Klaus, Coleman Amaziah T, Evans Michael D, Thorsen Jonathan, Waage Johannes, Vissing Nadja H, Carlsson Christian J, Stokholm Jakob, Chawes Bo L, Jessen Leon E, Fischer Thea K, Bochkov Yury A, Ober Carole, Lemanske Robert F, Jackson Daniel J, Gern James E, Bisgaard Hans
Abstract excerpt
RATIONALE: Experimental evidence suggests that CDHR3 (cadherin-related family member 3) is a receptor for rhinovirus (RV)-C, and a missense variant in this gene (rs6967330) is associated with childhood asthma with severe exacerbations. OBJECTIVES: To determine whether rs6967330 influences RV-C infections and illnesses in early childhood. METHODS: We studied associations between rs6967330 and respiratory...
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