Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations.

doi:10.1016/j.alit.2017.02.012

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Article

Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations.

Allergology international : official journal of the Japanese Society of Allergology - 1 Oct 2017

Kanazawa Jun, Masuko Hironori, Yatagai Yohei, Sakamoto Tohru, Yamada Hideyasu, Kaneko Yoshiko, Kitazawa Haruna, Iijima Hiroaki, Naito Takashi, Saito Takefumi, Noguchi Emiko, Konno Satoshi, Nishimura Masaharu, Hirota Tomomitsu, Tamari Mayumi, Hizawa Nobuyuki

Abstract excerpt

BACKGROUND: Recent studies have demonstrated that a coding SNP (rs6967330, Cys529→Tyr) in cadherin-related family member 3 (CDHR3), which was previously associated with wheezing illness and hospitalizations in infancy, could support efficient human rhinovirus C (RV-C) entry and replication. Here, we sought to examine the genetic contribution of this variant to the development of adult asthma. METHODS: We...

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Identifiers

PMID: 28318885
DOI: 10.1016/j.alit.2017.02.012

Genes

CDHR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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