Article
Multi-trait analysis for genome-wide association study of five psychiatric disorders.
Translational psychiatry - 30 Jun 2020
Wu Yulu, Cao Hongbao, Baranova Ancha, Huang Hailiang, Li Sheng, Cai Lei, Rao Shuquan, Dai Minhan, Xie Min, Dou Yikai, Hao Qinjian, Zhu Ling, Zhang Xiangrong, Yao Yin, Zhang Fuquan, Xu Mingqing, Wang Qiang
Abstract excerpt
We conducted a cross-trait meta-analysis of genome-wide association study on schizophrenia (SCZ) (n = 65,967), bipolar disorder (BD) (n = 41,653), autism spectrum disorder (ASD) (n = 46,350), attention deficit hyperactivity disorder (ADHD) (n = 55,374), and depression (DEP) (n = 688,809). After the meta-analysis, the number of genomic loci increased from 14 to 19 in ADHD, from 3 to 10 in ASD, from 45 to 57 in...
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