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Involvement of TGFBI-TAGLN axis in cancer stem cell property of head and neck squamous cell carcinoma

21 Mar 2024

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) is a significant healthcare burden globally. Previous research using single-cell transcriptome analysis identified TGFBI as a crucial marker for the partial-epithelial-mesenchymal transition (partial-EMT) program. However, the precise role of TGFBI in HNSCC progression remains unclear. Therefore, our study aimed to clarify the impact of TGFBI on the malignant behavior...

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PMID: 38514830
DOI: 10.1038/s41598-024-57478-0

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