Article
Improvement in HLA-C typing by a new sequence-specific oligonucleotides kit.
HLA - 1 Sept 2020
Cargou Marine, Ralazamahaleo Mamy, Blouin Laura, Guidicelli Gwendaline, Visentin Jonathan
Abstract excerpt
PCR-sequence-specific oligonucleotide (PCR-SSO) is commonly used for HLA-typing. We recently replaced LabType SSO HD kit for HLA-C typing with the XR kit (OneLambda, Inc.). We used 137 patients' samples representing unique most likely HLA-C allele combinations to compare these kits' performance. The XR kit decreased the number of allele ambiguities with a median of 26.1% (first to third quartiles 20% to 36.2%,...
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