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Article

Pharmacogenetics in the treatment of gastrointestinal stromal tumors - an updated review.

Expert opinion on drug metabolism & toxicology - 1 Sept 2020

Ravegnini Gloria, Valori Giorgia, Zhang Qianqian, Ricci Riccardo, Hrelia Patrizia, Angelini Sabrina

Abstract excerpt

INTRODUCTION: Gastrointestinal stromal tumors (GIST) are the best example of a targeted therapy in solid tumors. The introduction of tyrosine kinase inhibitors (TKIs) deeply improved the prognosis of this tumor. However, a degree of inter-patient variability is still reported in response rates and pharmacogenetics may play an important role in the final clinical outcome. AREAS COVERED: In this review, the authors...

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Identifiers

PMID: 32597248
DOI: 10.1080/17425255.2020.1789589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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