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Article

Exploration of gene expression profiles and immune microenvironment between high and low tumor mutation burden groups in prostate cancer.

International immunopharmacology - 1 Sept 2020

Luo Cheng, Chen Junxing, Chen Lingwu

Abstract excerpt

BACKGROUND: Tumor mutation burden (TMB) has been established as a biomarker for response to immune therapy and prognosis in various cancers. However, the association between TMB and prognosis of prostate cancer (PCa) remains unclear. This study aimed to investigate the impact of TMB in biochemical recurrence (BCR) and the immune microenvironment in high and low TMB groups. METHODS: Mutation data, gene expression,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32593155
DOI: 10.1016/j.intimp.2020.106709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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