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Article

Exploration of the Tumor Mutational Burden as a Prognostic Biomarker and Related Hub Gene Identification in Prostate Cancer.

Technology in cancer research & treatment - 1 Jan 2000

Wang Licheng, Yao Yicong, Xu Chengdang, Wang Xinan, Wu Denglong, Hong Zhe

Abstract excerpt

To explore the signature function of the tumor mutational burden (TMB) and potential biomarkers in prostate cancer (PCa), transcriptome profiles, somatic mutation data, and clinicopathologic feature information were downloaded from The Cancer Genome Atlas (TCGA) database. R software package was used to generate a waterfall plot to summarize the specific mutation information and calculate the TMB value of PCa....

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Identifiers

PMID: 34806485
DOI: 10.1177/15330338211052154
PMCID: PMC8606726

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