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Article

NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands.

Redox biology - 1 Sept 2020

Wati Sisca Meida, Matsumaru Daisuke, Motohashi Hozumi

Abstract excerpt

Saliva plays an essential role in the maintenance of oral health. The oral cavity environment changes during aging mainly due to alterations in the secretion and composition of saliva. In particular, unstimulated basal salivary flow decreases with age. The functional decline of the salivary glands impairs chewing and swallowing abilities and often becomes one of the predispositions for aging-related disorders,...

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Identifiers

PMID: 32590331
DOI: 10.1016/j.redox.2020.101603
PMCID: PMC7322188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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