Article
Mathematical modeling of PDGF-driven glioma reveals the dynamics of immune cells infiltrating into tumors.
Neoplasia (New York, N.Y.) - 1 Sept 2020
Niu Ben, Zeng Xianyi, Phan Tuan Anh, Szulzewsky Frank, Holte Sarah, Holland Eric C, Tian Jianjun Paul
Abstract excerpt
BACKGROUND: Tumor-infiltrated immune cells compose a significant component of many cancers. They have been observed to have contradictory impacts on tumors. Although the primary reasons for these observations remain elusive, it is important to understand how immune cells infiltrating into tumors is regulated. Recently our group conducted a series of experimental studies, which showed that muIDH1 gliomas have a...
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