Article
Genetic risk factors for lumbar disc disease.
Clinical anatomy (New York, N.Y.) - 1 Jan 2021
Doraisamy Ravichandran, Ramaswami Karthikeyan, Shanmugam Jeevithan, Subramanian Rashmi, Sivashankaran Balasubramanian
Abstract excerpt
AIM AND BACKGROUND: Lumbar disc degeneration (LDD) is thought to be multifactorial in origin. Very recently the focus has shifted to the involvement of a family of candidate genes in the pathogenesis of LDD. There is particular emphasis on the vitamin D receptor gene (VDR gene). The VDR polymorphisms FOK1, TAQ1, and APO1 have been variably associated with LDD. OBJECTIVE: To evaluate the association between the...
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