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Article

Influence of tumour suppressor gene (TP53, BRCA1 and BRCA2) polymorphisms on polycystic ovary syndrome in South Indian women.

European journal of obstetrics, gynecology, and reproductive biology - 1 Aug 2018

Siddamalla Swapna, Reddy Tumu Venkat, Govatati Suresh, Guruvaiah Praveen, Deenadayal Mamata, Shivaji Sisinthy, Bhanoori Manjula

Abstract excerpt

OBJECTIVE: Polycystic Ovary Syndrome (PCOS) is a heterogeneous multifactorial endocrine metabolic disorder. In addition to hyperandrogenism, acne, hirsutism, obesity, oligoanovulation and infertility, insulin resistance is also a common feature in women of PCOS. Tumor suppressor genes (TSGs) perform essential function in the maintenance of genomic stability and regulatory pathways influencing the activity of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29860059
DOI: 10.1016/j.ejogrb.2018.05.027

Genes

BRCA1
BRCA2

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