Association study of gene LPP in women with polycystic ovary syndrome.

Abstract excerpt

BACKGROUND: Previous genome-wide association study (GWAS) of polycystic ovary syndrome (PCOS) in Han Chinese population has found that SNPs in LPP gene were nominally significant in PCOS patients (P around 10E-05). Replication of the GWAS was applied to further confirm the relationship between LPP gene and PCOS. METHODS: Three polymorphisms of LPP gene (rs715790, rs4449306, rs6782041) were selected and replicated...