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Article

Untangling the effects of cellular composition on coexpression analysis.

Genome research - 1 Jun 2020

Farahbod Marjan, Pavlidis Paul

Abstract excerpt

Coexpression analysis is widely used for inferring regulatory networks, predicting gene function, and interpretation of transcriptome profiling studies, based on methods such as clustering. The majority of such studies use data collected from bulk tissue, where the effects of cellular composition present a potential confound. However, the impact of composition on coexpression analysis has not been studied in...

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Identifiers

PMID: 32580998
DOI: 10.1101/gr.256735.119
PMCID: PMC7370889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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