Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring Catalysis Specificity of Phytoene Dehydrogenase CrtI in Carotenoid Synthesis.

ACS synthetic biology - 17 Jul 2020

Liang Nan, Chen Chen, Wang Ying, Ding Ming-Zhu, Yao Ming-Dong, Xiao Wen-Hai, Yuan Ying-Jin

Abstract excerpt

Carotenoids, a variety of natural products, have significant pharmaceutical and commercial potential. Phytoene dehydrogenase (CrtI) is the rate-limit enzyme for carotenoid synthesis, whose catalysis specificity results in various carotenoids. However, the structural characteristics of CrtI for controlling the catalysis specificity on dehydrogenation steps are still unclear, which limited the development of CrtI...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to Biocatalysis
Share to Carotenoids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyanobacteria

Share to Oxidoreductases

Share to Plants

Share to Principal Component Analysis

Share to Substrate Specificity

Source

Identifiers

PMID: 32579850
DOI: 10.1021/acssynbio.0c00128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring Catalysis Specificity of Phytoene Dehydrogenase CrtI in Carotenoid Synthesis.PMID 32579850Read ↗

Compound mutagenesis boosts β-carotene biosynthesis in Neurospora crassa: ATP synthase mutation and enzymes activities enhancement.Semantic proximity Read ↗

Heterologous Expression of Ketoreductase ChKRED20 Mutant in Pichia pastoris and Bioreductive Production of (R)-1, 3-Butanediol.Semantic proximity Read ↗

Enzymatic Plasticity Inspired by the Diterpene Cyclase CotB2.Semantic proximity Read ↗

In silico characterization of the impact of mutation (LEU112PRO) on the structure and function of carotenoid cleavage dioxygenase 8 in Oryza sativa.Semantic proximity Read ↗

Evolution of the C30 carotenoid synthase CrtM for function in a C40 pathway.Semantic proximity Read ↗

β-Ionone: Its Occurrence and Biological Function and Metabolic EngineeringSemantic proximity Read ↗

PFDB: Polyphenol Family DatabaseSemantic proximity Read ↗

Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.Semantic proximity Read ↗

Rational design of a zinc-dependence secondary alcohol dehydrogenase to boost its oxidation activity for α-hydroxyketones biosynthesis.Semantic proximity Read ↗

Colorful World of Microbes: Carotenoids and Their ApplicationsSemantic proximity Read ↗

Computational and deep-learning-guided design of raspberry ketone synthase towards concurrent gains in activity and thermostability.Semantic proximity Read ↗

Transcriptome profiling of genes involving in carotenoid biosynthesis and accumulation between leaf and root of carrot (Daucus carota L.)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.