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Article

Emerging use of senolytics and senomorphics against aging and chronic diseases

24 Jun 2020

Abstract excerpt

Senescence is a state of cell cycle arrest that plays an important role in embryogenesis, wound healing and protection against cancer. Senescent cells also accumulate during aging and contribute to the development of age-related disorders and chronic diseases, such as atherosclerosis, type 2 diabetes, osteoarthritis, idiopathic pulmonary fibrosis, and liver disease. Molecules that induce apoptosis of senescent...

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PMID: 32578904
DOI: 10.1002/med.21702

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