Article
Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse
19 Dec 2013
Abstract excerpt
Patient derived xenografts (PDXs) are increasingly appreciated models in cancer research, particularly for preclinical testing, as they reflect the patient's tumor biology more accurately than cancer cell lines. We have established a collection of 20 breast PDXs and characterized their biological and clinical features, as well as their genetic stability. While most PDXs originated from triple negative breast...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.