Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation

22 Jun 2020

Abstract excerpt

is the causative agent of melioidosis, an infectious disease in the tropics and subtropics with high morbidity and mortality. The facultative intracellular bacterium induces host cell fusion through its type VI secretion system 5 (T6SS5) as an important part of its pathogenesis in mammalian hosts. This allows it to spread intercellularly without encountering extracellular host defenses. We report that bacterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Burkholderia infections and melioidosis
Share to interferon and immune responses
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32571920
DOI: 10.1073/pnas.2006908117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formationPMID 32571920Read ↗

SARS-CoV-2 spike protein–induced cell fusion activates the cGAS-STING pathway and the interferon responseSemantic proximity Read ↗

The interactions between cGAS-STING pathway and pathogensSemantic proximity Read ↗

cGAS‐STING signaling in cell death: Mechanisms of action and implications in pathologiesSemantic proximity Read ↗

Micronucleus Production, Activation of DNA Damage Response and cGAS-STING Signaling in Syncytia Induced by SARS-CoV-2 InfectionSemantic proximity Read ↗

Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infectionSemantic proximity Read ↗

The cGAS-STING pathway in viral infections: a promising link between inflammation, oxidative stress and autophagySemantic proximity Read ↗

The multifaceted functions of cGASSemantic proximity Read ↗

Somatic Cell Fusion in Host Defense and Adaptation.Semantic proximity Read ↗

Crosstalk Between Autophagy and the cGAS–STING Signaling Pathway in Type I Interferon ProductionSemantic proximity Read ↗

RNA viruses and the cGAS-STING pathway: reframing our understanding of innate immune sensingSemantic proximity Read ↗

Double-stranded RNA orbivirus disrupts the DNA-sensing cGAS-sting axis to prevent type I IFN inductionSemantic proximity Read ↗

How the Innate Immune DNA Sensing cGAS–STING Pathway Is Involved in AutophagySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.