Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Translesion DNA Synthesis and Carcinogenesis

1 Apr 2020

Abstract excerpt

Tens of thousands of DNA lesions are formed in mammalian cells each day. DNA translesion synthesis is the main mechanism of cell defense against unrepaired DNA lesions. DNA polymerases iota (Pol ι), eta (Pol η), kappa (Pol κ), and zeta (Pol ζ) have active sites that are less stringent toward the DNA template structure and efficiently incorporate nucleotides opposite DNA lesions. However, these polymerases display...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to DNA Repair Mechanisms
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32569550
DOI: 10.1134/s0006297920040033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Translesion DNA Synthesis and CarcinogenesisPMID 32569550Read ↗

Translesion synthesis DNA polymerases and control of genome stability.Semantic proximity Read ↗

Mechanisms of mutagenesis induced by DNA lesions: multiple factors affect mutations in translesion DNA synthesis.Semantic proximity Read ↗

Translesion and Repair DNA Polymerases: Diverse Structure and MechanismSemantic proximity Read ↗

[Advances of study on human translesion synthesis DNA polymerase eta].Semantic proximity Read ↗

Translesion DNA Synthesis and Reinitiation of DNA Synthesis in Chemotherapy ResistanceSemantic proximity Read ↗

A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ.Semantic proximity Read ↗

Translesion Synthesis across Abasic Lesions by Human B-Family and Y-Family DNA Polymerases α, δ, η, ι, κ, and REV1Semantic proximity Read ↗

How DNA lesions are turned into mutations within cells?Semantic proximity Read ↗

Translesion synthesis of O4-alkylthymidine lesions in human cells.Semantic proximity Read ↗

DNA repair: Polymerases for passing lesions.Semantic proximity Read ↗

DNA polymerase delta in dna replication and genome maintenanceSemantic proximity Read ↗

DNA repairSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.