Article
Prognosis and regulation of an adenylyl cyclase network in acute myeloid leukemia.
Aging - 22 Jun 2020
Chen Si-Liang, Hu Fang, Wang Da-Wei, Qin Zhe-Yuan, Liang Yang, Dai Yu-Jun
Abstract excerpt
We explored the roles of adenylyl cyclases (ADCYs) in acute myeloid leukemia (AML). Expression ADCYs in AML and their effect on prognosis was analyzed using data from Oncomine, GEPIA and cBioPortal databases. Frequently altered neighbor genes (FANGs) of ADCYs were detected using the 3D Genome Browser, after which the functions of these FANGs were predicted using Metascape tools. Cell viability and apoptosis were...
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