Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Gender-Dependent Patterns of Cardiac Fibrosis and Fibroblast Phenotypes in Aging Mice.

Oxidative medicine and cellular longevity - 1 Jan 2020

Achkar Angela, Saliba Youakim, Fares Nassim

Abstract excerpt

Aging is characterized by physiological changes within the heart leading to fibrosis and dysfunction even in individuals without underlying pathologies. Gender has been shown to influence the characteristics of cardiac aging; however, gender-dependent cardiac fibrosis occurring with age remains largely not elucidated. Thus, broadening our understanding of this phenomenon proves necessary in order to develop novel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Collagen
Share to Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrosis

Share to Models, Cardiovascular

Share to Myocardium

Share to Sex Characteristics

Share to Ventricular Remodeling

Source

Open in PubMed Open full text

Identifiers

PMID: 32566103
DOI: 10.1155/2020/8282157
PMCID: PMC7267867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Gender-Dependent Patterns of Cardiac Fibrosis and Fibroblast Phenotypes in Aging Mice.PMID 32566103Read ↗

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice.Semantic proximity Read ↗

The Role of Cardiac Fibroblast Heterogeneity in Myocardial Fibrosis and Its Novel Therapeutic PotentialSemantic proximity Read ↗

Changes in cardiac resident fibroblast physiology and phenotype in aging.Semantic proximity Read ↗

Sex-Specific Characterization of a Novel Osteoarthritis-Induced Heart Failure Model in MiceSemantic proximity Read ↗

Comparative phenotyping of C57BL/6J substrains reveals distinctive patterns of cardiac aging.Semantic proximity Read ↗

Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis.Semantic proximity Read ↗

Cardiac Fibroblast DiversitySemantic proximity Read ↗

Age-related changes in tissue macrophages precede cardiac functional impairmentSemantic proximity Read ↗

The Senescent Heart—“Age Doth Wither Its Infinite Variety”Semantic proximity Read ↗

Cardiac remodeling in the mouse model of Marfan syndrome develops into two distinctive phenotypes.Semantic proximity Read ↗

Control of cardiac remodelling during ageing and disease by epigenetic modifications and modifiersSemantic proximity Read ↗

Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.