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Article

Association between an indel polymorphism within CTH and the risk of sudden cardiac death in a Chinese population.

Legal medicine (Tokyo, Japan) - 1 Sept 2020

Zhou Wei, Yang Qi, Yu Huan, Zhang Qing, Zou Yan, Chen Xuekun, Yang Zhenzhen, Qu Yiling, Tan Rui, Li Lijuan, Zhu Shaohua, He Yan, Luo Bin, Gao Yuzhen

Abstract excerpt

Individuals harbouring specific genetic variations might trend towards suffering sudden cardiac death. Cystathionine-γ-lyase is one of the key enzymes of endogenous hydrogen sulfide production, and a key factor on the expression regulation of hydrogen sulfide in human heart. Compelling studies have suggested the cardioprotective effects of hydrogen sulfide, while it remains controversial whether...

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PMID: 32563979
DOI: 10.1016/j.legalmed.2020.101736

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