Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations Between IFI44L Gene Variants and Rates of Respiratory Tract Infections During Early Childhood.

The Journal of infectious diseases - 4 Jan 2021

Lempainen Johanna, Korhonen Laura S, Kantojärvi Katri, Heinonen Santtu, Toivonen Laura, Räty Panu, Ramilo Octavio, Mejias Asuncion, Laine Antti-Pekka, Vuorinen Tytti, Waris Matti, Karlsson Linnea, Karlsson Hasse, Paunio Tiina, Peltola Ville

Abstract excerpt

BACKGROUND: Genetic heterogeneity in type I interferon (IFN)-related gene IFI44L may account for variable susceptibility to respiratory tract infections (RTIs) in children. METHODS: In 2 prospective, population-based birth cohorts, the STEPS Study and the FinnBrain Birth Cohort Study, IFI44L genotypes for rs273259 and rs1333969 were determined in relation to the development of RTIs until 1 or 2 years of age,...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Genetic Predisposition to Disease
Share to Infant
Share to Otitis Media
Share to Polymorphism, Single Nucleotide
Share to Respiratory Tract Infections
Share to Rhinovirus
Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 32561935
DOI: 10.1093/infdis/jiaa341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations Between IFI44L Gene Variants and Rates of Respiratory Tract Infections During Early Childhood.PMID 32561935Read ↗

Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes.Semantic proximity Read ↗

IFN-λ4 is associated with increased risk and earlier occurrence of several common infections in African children.Semantic proximity Read ↗

Gene polymorphism of IFNG +874 T/A and TLR4 +896 A/G and recurrent infections and wheezing in toddlers with history of bronchiolitis.Semantic proximity Read ↗

Polymorphisms of immunity genes and susceptibility to otitis media in children.Semantic proximity Read ↗

Polymorphisms in the IRF-4 gene, asthma and recurrent bronchitis in children.Semantic proximity Read ↗

Severe viral respiratory infections in children with IFIH1 loss-of-function mutations.Semantic proximity Read ↗

Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial VirusSemantic proximity Read ↗

Association of Asthma Risk Alleles With Acute Respiratory Tract Infections and Wheezing Illnesses in Young Children.Semantic proximity Read ↗

IFN-λ4 is associated with increased risk and earlier occurrence of gastrointestinal, respiratory and malarial infections in Malian childrenSemantic proximity Read ↗

Interactions Between Innate Immunity Genes and Early-Life Risk Factors in Allergic RhinitisSemantic proximity Read ↗

Nasal IFN and UPR Transcriptomic Signatures Complement Clinical Predictors of Frequent Exacerbations in Pediatric AsthmaSemantic proximity Read ↗

Association of common single-nucleotide polymorphisms in innate immune genes with differences in TLR-induced cytokine production in neonates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.