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Article

Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche.

Integrative biology : quantitative biosciences from nano to macro - 10 Jul 2020

Gilchrist Aidan E, Harley Brendan A C

Abstract excerpt

Hematopoietic stem cells (HSCs) primarily reside in the bone marrow, where they receive external cues from their local microenvironment. The complex milieu of biophysical cues, cellular components and cell-secreted factors regulates the process by which HSC produce the blood and immune system. We previously showed direct coculture of primary murine hematopoietic stem and progenitor cells with a population of...

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Identifiers

PMID: 32556172
DOI: 10.1093/intbio/zyaa013
PMCID: PMC7384206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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