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Article

Identification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscle

17 Apr 2014

Abstract excerpt

Fatty and fibrous connective tissue formation is a hallmark of diseased skeletal muscle and deteriorates muscle function. We previously identified non-myogenic mesenchymal progenitors that contribute to adipogenesis and fibrogenesis in mouse skeletal muscle. In this study, we report the identification and characterization of a human counterpart to these progenitors. By using PDGFRα as a specific marker,...

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PMID: 24743741
DOI: 10.1038/cddis.2014.161

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