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Article

Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose Homeostasis

24 Oct 2014

Abstract excerpt

Adipose tissues have striking plasticity, highlighted by childhood and adult obesity. Using adipose lineage analyses, smooth muscle actin (SMA)-mural cell-fate mapping, and conditional PPARγ deletion to block adipocyte differentiation, we find two phases of adipocyte generation that emanate from two independent adipose progenitor compartments: developmental and adult. These two compartments are sequentially...

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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25437556
DOI: 10.1016/j.celrep.2014.09.049

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