Influence of CYP3A5 Genetic Polymorphism on Long-Term Renal Function in Chinese Kidney Transplant Recipients Using Limited Sampling Strategy and Abbreviated Area Under the Curve for Tacrolimus Monitoring.

Abstract excerpt

INTRODUCTION: Although the association between CYP3A5 gene polymorphism and tacrolimus dosing requirements was well established, the impact on how CYP3A5 genotype affects the acute rejection and long-term renal function in patients who received kidney transplants and were treated with tacrolimus remained controversial. DESIGN: Sixty-seven Chinese patients with kidney transplants receiving de novo tacrolimus-based...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Area Under Curve
• Share to Cytochrome P-450 CYP3A