Article
Association between bacterial homoplastic variants and radiological pathology in tuberculosis.
Thorax - 1 Jul 2020
Grandjean Louis, Monteserin Joha, Gilman Robert, Pauschardt Julia, Rokadiya Sakib, Bonilla Cesar, Ritacco Viviana, Vidal Julia Rios, Parkhill Julian, Peacock Sharon, Moore David Aj, Balloux Francois
Abstract excerpt
BACKGROUND: Understanding how pathogen genetic factors contribute to pathology in TB could enable tailored treatments to the most pathogenic and infectious strains. New strategies are needed to control drug-resistant TB, which requires longer and costlier treatment. We hypothesised that the severity of radiological pathology on the chest radiograph in TB disease was associated with variants arising independently,...
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