Article
Polymorphisms of the receptor for advanced glycation end products as vasculopathy predictor in sickle cell disease.
Pediatric research - 1 Jan 2021
Safwat Nesma Ahmed, ELkhamisy Mai Mohamed, Abdel-Wahab Soha Ezz AlArab, Hamza Mohamed Tarif, Boshnak Noha Hussein, Kenny Mahmoud Adel
Abstract excerpt
BACKGROUND: The genetic variants of the receptor for advanced glycation end products (RAGE) gene have been associated with vascular disease risk. The objective of this work was to explore the association of three single-nucleotide polymorphisms (SNPs) of RAGE gene (374T/A, 429T/C, and G82S) with vascular complications in SCD. METHODS: The study was conducted on 40 children with SCD and 40 healthy children served...
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