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Article

A Case of APC Gene Mutation-Associated Familial Adenomatous Polyposis With Multiple System Malignancies.

Cancer reports (Hoboken, N.J.) - 1 Oct 2025

Yijing Ren, Wenjun Wang, Xiang Gao, Kongling Xing, Yunxia Chen, Wei Liao, Ping Zhou

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disorder, with a nearly 100% risk of developing colorectal cancer by the age of 40. The primary gene mutated in FAP is APC, and mutations in certain regions of the APC gene may be associated with thyroid disorders, including malignant neoplasms, benign nodules, and endocrine diseases of the thyroid. FAP-associated colorectal...

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Topics

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Share to Adenomatous Polyposis Coli
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, APC

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Share to Neoplasms, Multiple Primary

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Source

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Identifiers

PMID: 41104667
DOI: 10.1002/cnr2.70362
PMCID: PMC12531898

Genes

APC
FAP
MUTYH

Variants

Provenance

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