Article
Vitamin D endocrine system and the genetic susceptibility to diabetes, obesity and vascular disease. A review of evidence.
Diabetes & metabolism - 1 Sept 2005
Reis A F, Hauache O M, Velho G
Abstract excerpt
The Vitamin D endocrine system regulates multiple aspects of calcium metabolism and cellular differentiation and replication in the immune system, endocrine pancreas, liver, skeletal muscles and adipocytes. It plays an important role in glucose homeostasis, notably, in the mechanism of insulin release. Actions of vitamin D are mediated by the binding of 1, 25-(OH)2D3 to a specific cytosolic/nuclear vitamin D...
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