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Article

Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development.

Journal of visualized experiments : JoVE - 28 May 2020

Wang Yong, Zhang Ding, Zhou Fang, Zhou Meijun, Li Qiujie, Chen Jingyu, Yang Jun

Abstract excerpt

Vascular development is determined by the sequential expression of specific genes, which can be studied by performing in situ hybridization assays in zebrafish during different developmental stages. To investigate the role of endoglin(eng) in vessel formation during the development of hereditary hemorrhagic telangiectasia (HHT), morpholino-mediated targeted knockdown of eng in zebrafish are used to study its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32538908
DOI: 10.3791/60498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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