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Oocyte development, meiosis and aneuploidy

1 Sept 2015

Abstract excerpt

Meiosis is one of the defining events in gametogenesis. Male and female germ cells both undergo one round of meiotic cell division during their development in order to reduce the ploidy of the gametes, and thereby maintain the ploidy of the species after fertilisation. However, there are some aspects of meiosis in the female germline, such as the prolonged arrest in dictyate, that appear to predispose oocytes to...

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PMID: 26454098
DOI: 10.1016/j.semcdb.2015.10.005

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