Article
Evolution of the Plasmodium vivax multidrug resistance 1 gene in the Greater Mekong Subregion during malaria elimination.
Parasites & vectors - 12 Feb 2020
Ngassa Mbenda Huguette Gaelle, Wang Meilian, Guo Jian, Siddiqui Faiza Amber, Hu Yue, Yang Zhaoqing, Kittichai Veerayuth, Sattabongkot Jetsumon, Cao Yaming, Jiang Lubin, Cui Liwang
Abstract excerpt
BACKGROUND: The malaria elimination plan of the Greater Mekong Subregion (GMS) is jeopardized by the increasing number of Plasmodium vivax infections and emergence of parasite strains with reduced susceptibility to the frontline drug treatment chloroquine/primaquine. This study aimed to determine the evolution of the P. vivax multidrug resistance 1 (Pvmdr1) gene in P. vivax parasites isolated from the...
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