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Article

Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)

10 Jun 2020

Abstract excerpt

The conversion of white adipocytes to thermogenic beige adipocytes represents a potential mechanism to treat obesity and related metabolic disorders. However, the mechanisms involved in converting white to beige adipose tissue remain incompletely understood. Here we show profound beiging in a genetic mouse model lacking the transcriptional repressor Krüppel-like factor 3 (KLF3). Bone marrow transplants from these...

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Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
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PMID: 32523103
DOI: 10.1038/s41467-020-16758-9

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