Article

Discovery and functional assessment of a novel adipocyte population driven by intracellular Wnt/β-catenin signaling in mammals

2021-01-16

Abstract excerpt

<h4>ABSTRACT</h4> Wnt/β-catenin signaling has been well established as a potent inhibitor of adipogenesis. Here, we identified a population of adipocytes that exhibit persistent activity of Wnt/β-catenin signaling, as revealed by the Tcf / Lef-Gfp reporter allele, in embryonic and adult mouse fat depots, named as Wnt + adipocytes. We showed that the β-catenin-mediated signaling activation in these cells is Wnt...

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Literature Corpus work: cd8bcd25-6588-5897-8ea2-ed7bda3cb7b6
DOI: 10.1101/2021.01.14.426702

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