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Article

Host dependent maintenance of a blaNDM-1-encoding plasmid in clinical Escherichia coli isolates

9 Jun 2020

Abstract excerpt

Dissemination of bacterial clones carrying plasmid-mediated resistance genes is a major factor contributing to the increasing prevalence of antibiotic resistance. Understanding the evolution of successful clones and the association to mobile resistance elements are therefore crucial. In this study, we determined the sequence of a 145 kb IncC multi-drug resistance plasmid (pK71-77-1-NDM), harbouring resistance...

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PMID: 32518312
DOI: 10.1038/s41598-020-66239-8

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