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Article

GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in Hepatocyte Nuclear Factor 1α Mutation Carriers.

Diabetes - 1 Sept 2020

Christensen Alexander S, Hædersdal Sofie, Storgaard Heidi, Rose Kathrine, Hansen Nina L, Holst Jens J, Hansen Torben, Knop Filip K, Vilsbøll Tina

Abstract excerpt

Sulfonylureas (SUs) provide an efficacious first-line treatment in patients with hepatocyte nuclear factor 1α (HNF1A) diabetes, but SUs have limitations due to risk of hypoglycemia. Treatment based on the incretin hormones glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide 1 (GLP-1) is characterized by their glucose-dependent insulinotropic actions without risk of hypoglycemia. The effect of...

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Identifiers

PMID: 32518064
DOI: 10.2337/db20-0074
PMCID: PMC7458039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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