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Article

Elements of the Endomucin Extracellular Domain Essential for VEGF-Induced VEGFR2 Activity.

Cells - 5 Jun 2020

Hu Zhengping, Cano Issahy, Saez-Torres Kahira L, LeBlanc Michelle E, Saint-Geniez Magali, Ng Yin-Shan, Argüeso Pablo, D'Amore Patricia A

Abstract excerpt

Endomucin (EMCN) is the type I transmembrane glycoprotein, mucin-like component of the endothelial cell glycocalyx. We have previously shown that EMCN is necessary for vascular endothelial growth factor (VEGF)-induced VEGF receptor 2 (VEGFR2) internalization and downstream signaling. To explore the structural components of EMCN that are necessary for its function and the molecular mechanism of EMCN in...

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Identifiers

PMID: 32517158
DOI: 10.3390/cells9061413
PMCID: PMC7349057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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