Article
The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence.
Molecular medicine reports - 1 Mar 2013
Peng Dan, Zuo Houjuan, Liu Zhengxiang, Qin Jin, Zhou Yuanlin, Li Pengcheng, Wang Daowen, Zeng Hesong, Zhang Xin A
Abstract excerpt
Previous studies have shown that the tetraspanin CD151 is essential for pathological or physiological angiogenesis. However, the cellular signaling mechanism and the role of the CD151 YRSL sorting motif in in vitro vasculogenesis remains unknown. In this study, the results showed that both CD151 and CD151-ARSA gene delivery were capable of increasing the expression...
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