Back to search

Article

A CpGs Methylation Signature as Potential Marker for Early Diagnosis of Hepatocellular Carcinoma from HBV-Related Liver Disease using Multiplex Bisulfite Sequencing

2021-07-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Aberrant methylation of CpG sites severed as epigenetic marker for building diagnostic, prognostic, and recurrence models for hepatocellular carcinoma (HCC). <bold>Methods:</bold>Using Illumina 450K and EPIC Beadchip, we identified 34 CpG sites in peripheral blood mononuclear cell(PBMC) DNA that were differentially methylatedin early HCCversusHBV-related liver d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
53ac9f52-4364-5cd5-b699-5ccb4773f24a
DOI
10.21203/rs.3.rs-743735/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A CpGs Methylation Signature as Potential Marker for Early Diagnosis of Hepatocellular Carcinoma from HBV-Related Liver Disease using Multiplex Bisulfite SequencingDOI 10.21203/rs.3.rs-743735/v1
The signature of HBV-related liver disease in peripheral blood mononuclear cell DNA methylationSemantic proximity
Genome‐wide identification of blood DNA methylation patterns associated with early‐onset hepatocellular carcinoma development in hepatitis B carriersSemantic proximity
Early detection and prognosis evaluation for hepatocellular carcinoma by circulating tumour DNA methylation: A multicentre cohort studySemantic proximity
Clinical validation of peripheral blood mononuclear cell DNA methylation markers for accurate early detection of hepatocellular carcinoma in Asian patientsSemantic proximity
<i>epi</i>Liver a novel tumor specific, high throughput and cost-effective blood test for specific detection of liver cancer (HCC)Semantic proximity
CpG Methylation Signature Predicts Recurrence in Early-Stage Hepatocellular Carcinoma: Results From a Multicenter StudySemantic proximity
epiLiver a novel tumor specific, high throughput and cost-effective blood test for specific detection of liver cancer (HCC)Semantic proximity
DNA methylation fingerprint for the diagnosis and monitoring of hepatocellular carcinoma from tissue and liquid biopsiesSemantic proximity
Hepatocellular Carcinoma Displays Distinct DNA Methylation Signatures with Potential as Clinical PredictorsSemantic proximity
Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinomaSemantic proximity
Comprehensive review and updated analysis of DNA methylation in hepatocellular carcinoma: From basic research to clinical applicationSemantic proximity
HepaClear, a blood-based panel combining novel methylated CpG sites and protein markers, for the detection of early-stage hepatocellular carcinomaSemantic proximity
Select a neighboring publication to make it the new centre.